Novel N-Substituted 3-Aryl-4-(diethoxyphosphoryl)azetidin-2-ones as Antibiotic Enhancers and Antiviral Agents in Search for a Successful Treatment of Complex Infections

A novel series of N-substituted cis- and trans-3-aryl-4-(diethoxyphosphoryl)azetidin-2-ones were synthesized by the Kinugasa reaction of N-methyl- or N-benzyl-(diethyoxyphosphoryl)nitrone and selected aryl alkynes. Stereochemistry of diastereoisomeric adducts was established based on vicinal H3–H4 c...

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Detalles Bibliográficos
Autores principales: Głowacka, Iwona E., Grabkowska-Drużyc, Magdalena, Andrei, Graciela, Schols, Dominique, Snoeck, Robert, Witek, Karolina, Podlewska, Sabina, Handzlik, Jadwiga, Piotrowska, Dorota G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348901/
https://www.ncbi.nlm.nih.gov/pubmed/34360797
http://dx.doi.org/10.3390/ijms22158032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348901/
https://www.ncbi.nlm.nih.gov/pubmed/34360797
http://dx.doi.org/10.3390/ijms22158032

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