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Novel N-Substituted 3-Aryl-4-(diethoxyphosphoryl)azetidin-2-ones as Antibiotic Enhancers and Antiviral Agents in Search for a Successful Treatment of Complex Infections
A novel series of N-substituted cis- and trans-3-aryl-4-(diethoxyphosphoryl)azetidin-2-ones were synthesized by the Kinugasa reaction of N-methyl- or N-benzyl-(diethyoxyphosphoryl)nitrone and selected aryl alkynes. Stereochemistry of diastereoisomeric adducts was established based on vicinal H3–H4 c...
Autores principales: | Głowacka, Iwona E., Grabkowska-Drużyc, Magdalena, Andrei, Graciela, Schols, Dominique, Snoeck, Robert, Witek, Karolina, Podlewska, Sabina, Handzlik, Jadwiga, Piotrowska, Dorota G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348901/ https://www.ncbi.nlm.nih.gov/pubmed/34360797 http://dx.doi.org/10.3390/ijms22158032 |
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