Exploration of Novel Xanthine Oxidase Inhibitors Based on 1,6-Dihydropyrimidine-5-Carboxylic Acids by an Integrated in Silico Study

Xanthine oxidase (XO) is an important target for the effective treatment of hyperuricemia-associated diseases. A series of novel 2-substituted 6-oxo-1,6-dihydropyrimidine-5-carboxylic acids (ODCs) as XO inhibitors (XOIs) with remarkable activities have been reported recently. To better understand th...

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Detalles Bibliográficos
Autores principales: Zhai, Na, Wang, Chenchen, Wu, Fengshou, Xiong, Liwei, Luo, Xiaogang, Ju, Xiulian, Liu, Genyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348919/
https://www.ncbi.nlm.nih.gov/pubmed/34360886
http://dx.doi.org/10.3390/ijms22158122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348919/
https://www.ncbi.nlm.nih.gov/pubmed/34360886
http://dx.doi.org/10.3390/ijms22158122

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