Amaryllidaceae Alkaloids of Norbelladine-Type as Inspiration for Development of Highly Selective Butyrylcholinesterase Inhibitors: Synthesis, Biological Activity Evaluation, and Docking Studies

Alzheimer’s disease (AD) is a multifactorial neurodegenerative condition of the central nervous system (CNS) that is currently treated by cholinesterase inhibitors and the N-methyl-d-aspartate receptor antagonist, memantine. Emerging evidence strongly supports the relevance of targeting butyrylcholi...

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Detalles Bibliográficos
Autores principales: Mamun, Abdullah Al, Pidaný, Filip, Hulcová, Daniela, Maříková, Jana, Kučera, Tomáš, Schmidt, Monika, Catapano, Maria Carmen, Hrabinová, Martina, Jun, Daniel, Múčková, Lubica, Kuneš, Jiří, Janoušek, Jiří, Andrýs, Rudolf, Nováková, Lucie, Peřinová, Rozálie, Maafi, Negar, Soukup, Ondřej, Korábečný, Jan, Cahlíková, Lucie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348983/
https://www.ncbi.nlm.nih.gov/pubmed/34361074
http://dx.doi.org/10.3390/ijms22158308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348983/
https://www.ncbi.nlm.nih.gov/pubmed/34361074
http://dx.doi.org/10.3390/ijms22158308

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