Identification of lead compounds from large natural product library targeting 3C-like protease of SARS-CoV-2 using E-pharmacophore modelling, QSAR and molecular dynamics simulation

COVID-19 is a novel disease caused by SARS-CoV-2 and has made a catastrophic impact on the global economy. As it is, there is no officially FDA approved drug to alleviate the negative impact of SARS-CoV-2 on human health. Numerous drug targets for neutralizing coronavirus infection have been identif...

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Detalles Bibliográficos
Autores principales: Elekofehinti, Olusola Olalekan, Iwaloye, Opeyemi, Molehin, Olorunfemi R., Famusiwa, Courage D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349134/
https://www.ncbi.nlm.nih.gov/pubmed/34395160
http://dx.doi.org/10.1007/s40203-021-00109-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349134/
https://www.ncbi.nlm.nih.gov/pubmed/34395160
http://dx.doi.org/10.1007/s40203-021-00109-7

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