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Naloxone Protects against Lipopolysaccharide-Induced Neuroinflammation and Microglial Activation via Inhibiting ATP-Sensitive Potassium Channel

AIM: The aim of this study was to evaluate the anti-inflammatory effects and underlying mechanism of naloxone on lipopolysaccharide- (LPS-) induced neuronal inflammation and microglial activation. METHODS: LPS-treated microglial BV-2 cells and mice were used to investigate the anti-inflammatory effe...

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Detalles Bibliográficos
Autores principales: Tang, Zhijia, Shao, Xiaobao, Wu, Jun, Chen, Hucheng, Zhang, Anyu, Xu, Fei, Ping, He, Li, Shiwei, Liu, Chunyan, Li, Yijun, Xue, Xue, Yuan, Binbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349287/
https://www.ncbi.nlm.nih.gov/pubmed/34373698
http://dx.doi.org/10.1155/2021/7731528