Ursodeoxycholic acid suppresses the malignant progression of colorectal cancer through TGR5-YAP axis

The Hippo/YAP pathway plays an important role in the development of cancers. Previous studies have reported that bile acids can activate YAP (Yes Associated Protein) to promote tumorigenesis and tumor progression. Ursodeoxycholic acid (UDCA) is a long-established old drug used for cholestasis treatm...

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Detalles Bibliográficos
Autores principales: Zhang, Huan, Xu, Huanji, Zhang, Chenliang, Tang, Qiulin, Bi, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349355/
https://www.ncbi.nlm.nih.gov/pubmed/34365464
http://dx.doi.org/10.1038/s41420-021-00589-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349355/
https://www.ncbi.nlm.nih.gov/pubmed/34365464
http://dx.doi.org/10.1038/s41420-021-00589-8

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