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Ursodeoxycholic acid suppresses the malignant progression of colorectal cancer through TGR5-YAP axis
The Hippo/YAP pathway plays an important role in the development of cancers. Previous studies have reported that bile acids can activate YAP (Yes Associated Protein) to promote tumorigenesis and tumor progression. Ursodeoxycholic acid (UDCA) is a long-established old drug used for cholestasis treatm...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349355/ https://www.ncbi.nlm.nih.gov/pubmed/34365464 http://dx.doi.org/10.1038/s41420-021-00589-8 |