Histone deacetylase 2 knockout suppresses immune escape of triple-negative breast cancer cells via downregulating PD-L1 expression

The PD-L1 overexpression is an important event of immune escape and metastasis in triple-negative breast cancer (TNBC), but the molecular mechanism remains to be determined. Interferon gamma (IFNγ) represents a major driving force behind PD-L1 expression in tumor microenvironment, and histone deacet...

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Detalles Bibliográficos
Autores principales: Xu, Pengfei, Xiong, Wei, Lin, Yun, Fan, Liping, Pan, Hongchao, Li, Yaochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349356/
https://www.ncbi.nlm.nih.gov/pubmed/34365463
http://dx.doi.org/10.1038/s41419-021-04047-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349356/
https://www.ncbi.nlm.nih.gov/pubmed/34365463
http://dx.doi.org/10.1038/s41419-021-04047-2

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