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Histone deacetylase 2 knockout suppresses immune escape of triple-negative breast cancer cells via downregulating PD-L1 expression
The PD-L1 overexpression is an important event of immune escape and metastasis in triple-negative breast cancer (TNBC), but the molecular mechanism remains to be determined. Interferon gamma (IFNγ) represents a major driving force behind PD-L1 expression in tumor microenvironment, and histone deacet...
Autores principales: | Xu, Pengfei, Xiong, Wei, Lin, Yun, Fan, Liping, Pan, Hongchao, Li, Yaochen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349356/ https://www.ncbi.nlm.nih.gov/pubmed/34365463 http://dx.doi.org/10.1038/s41419-021-04047-2 |
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