The Antitumor Activity of CAR-T-PD1 Cells Enhanced by HPV16mE7-Pulsed and SOCS1-Silenced DCs in Cervical Cancer Models

BACKGROUND: Genetically T cells modified with cancer-specific chimeric antigen receptors (CARs) showed great promise in mediate tumor regression, especially in patients with advanced leukemia. However, the therapeutic effect against solid tumors is not as prominent as anticipated to exhibit potent a...

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Detalles Bibliográficos
Autores principales: Zheng, Jingwei, Huang, Jingsong, Ma, Wei, Yang, Wenqiang, Hu, Bicheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349543/
https://www.ncbi.nlm.nih.gov/pubmed/34377023
http://dx.doi.org/10.2147/CMAR.S321402

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349543/
https://www.ncbi.nlm.nih.gov/pubmed/34377023
http://dx.doi.org/10.2147/CMAR.S321402

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