Condensation of pericentrin proteins in human cells illuminates phase separation in centrosome assembly

At the onset of mitosis, centrosomes expand the pericentriolar material (PCM) to maximize their microtubule-organizing activity. This step, termed centrosome maturation, ensures proper spindle organization and faithful chromosome segregation. However, as the centrosome expands, how PCM proteins are...

Descripción completa

Detalles Bibliográficos
Autores principales: Jiang, Xueer, Ho, Dac Bang Tam, Mahe, Karan, Mia, Jennielee, Sepulveda, Guadalupe, Antkowiak, Mark, Jiang, Linhao, Yamada, Soichiro, Jao, Li-En
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349556/
https://www.ncbi.nlm.nih.gov/pubmed/34308971
http://dx.doi.org/10.1242/jcs.258897

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349556/
https://www.ncbi.nlm.nih.gov/pubmed/34308971
http://dx.doi.org/10.1242/jcs.258897

Ejemplares similares