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Condensation of pericentrin proteins in human cells illuminates phase separation in centrosome assembly
At the onset of mitosis, centrosomes expand the pericentriolar material (PCM) to maximize their microtubule-organizing activity. This step, termed centrosome maturation, ensures proper spindle organization and faithful chromosome segregation. However, as the centrosome expands, how PCM proteins are...
Autores principales: | Jiang, Xueer, Ho, Dac Bang Tam, Mahe, Karan, Mia, Jennielee, Sepulveda, Guadalupe, Antkowiak, Mark, Jiang, Linhao, Yamada, Soichiro, Jao, Li-En |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349556/ https://www.ncbi.nlm.nih.gov/pubmed/34308971 http://dx.doi.org/10.1242/jcs.258897 |
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