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Thymopentin alleviates premature ovarian failure in mice by activating YY2/Lin28A and inhibiting the expression of let‐7 family microRNAs

OBJECTIVE: Thymopentin (5TP) significantly improved typical murine premature ovarian failure (POF) symptoms induced by a high‐fat and high‐sugar (HFHS) diet. However, its effect and mechanism remain unclear. MATERIALS AND METHODS: RNA‐Seq was used to detect the differentially expressed genes among e...

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Detalles Bibliográficos
Autores principales: Liu, Te, Jing, Fangyuan, Huang, Peirong, Geng, Zixiang, Xu, Jianghong, Li, Jiahui, Chen, Danping, Zhu, Ying, Wang, Zhenxin, Huang, Willian, Chen, Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349654/
https://www.ncbi.nlm.nih.gov/pubmed/34180104
http://dx.doi.org/10.1111/cpr.13089