Human iPSC‐derived neural precursor cells differentiate into multiple cell types to delay disease progression following transplantation into YAC128 Huntington's disease mouse model

OBJECTIVES: To investigate whether human HLA‐homozygous induced pluripotent stem cell (iPSC)‐derived neural precursor cells (iPSC‐NPCs) can provide functional benefits in Huntington’s disease (HD), we transplanted them into the YAC128 transgenic HD mouse model. MATERIALS AND METHODS: CHAi001‐A, an H...

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Detalles Bibliográficos
Autores principales: Park, Hyun Jung, Jeon, Juhyun, Choi, Jiwoo, Kim, Ji Yeon, Kim, Hyun Sook, Huh, Ji Young, Goldman, Steven A., Song, Jihwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349664/
https://www.ncbi.nlm.nih.gov/pubmed/34152047
http://dx.doi.org/10.1111/cpr.13082

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349664/
https://www.ncbi.nlm.nih.gov/pubmed/34152047
http://dx.doi.org/10.1111/cpr.13082

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