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Cryptic amyloidogenic regions in intrinsically disordered proteins: Function and disease association

The amyloid conformation is considered a fundamental state of proteins and the propensity to populate it a generic property of polypeptides. Multiple proteome-wide analyses addressed the presence of amyloidogenic regions in proteins, nurturing our understanding of their nature and biological implica...

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Detalles Bibliográficos
Autores principales: Santos, Jaime, Pallarès, Irantzu, Iglesias, Valentín, Ventura, Salvador
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349759/
https://www.ncbi.nlm.nih.gov/pubmed/34527192
http://dx.doi.org/10.1016/j.csbj.2021.07.019