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Mutperiod: Analysis of periodic mutation rates in nucleosomes

Nucleosomes modulate DNA damage and repair, resulting in periodic mutation rates in nucleosomal DNA. Previous research has characterized these patterns in many sequenced tumor genomes; however, computational tools to identify and quantify these periodicities have not been developed for the broader s...

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Detalles Bibliográficos
Autores principales: Morledge-Hampton, Benjamin, Wyrick, John J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349767/
https://www.ncbi.nlm.nih.gov/pubmed/34527191
http://dx.doi.org/10.1016/j.csbj.2021.07.025