Cargando…
Mutperiod: Analysis of periodic mutation rates in nucleosomes
Nucleosomes modulate DNA damage and repair, resulting in periodic mutation rates in nucleosomal DNA. Previous research has characterized these patterns in many sequenced tumor genomes; however, computational tools to identify and quantify these periodicities have not been developed for the broader s...
Autores principales: | Morledge-Hampton, Benjamin, Wyrick, John J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349767/ https://www.ncbi.nlm.nih.gov/pubmed/34527191 http://dx.doi.org/10.1016/j.csbj.2021.07.025 |
Ejemplares similares
-
Nucleosome positions establish an extended mutation signature in melanoma
por: Brown, Alexander J., et al.
Publicado: (2018) -
Genome-wide maps of rare and atypical UV photoproducts reveal distinct patterns of damage formation and mutagenesis in yeast chromatin
por: Bohm, Kaitlynne A., et al.
Publicado: (2023) -
Molecular mechanism of UV damage modulation in nucleosomes
por: Stark, Bastian, et al.
Publicado: (2022) -
Asymmetric repair of UV damage in nucleosomes imposes a DNA strand polarity on somatic mutations in skin cancer
por: Mao, Peng, et al.
Publicado: (2020) -
Categorical spectral analysis of periodicity in nucleosomal DNA
por: Jin, Hu, et al.
Publicado: (2016)