Mapping of m(6)A and Its Regulatory Targets in Prostate Cancer Reveals a METTL3-Low Induction of Therapy Resistance

Recent evidence has highlighted the role of N(6)-methyladenosine (m(6)A) in the regulation of mRNA expression, stability, and translation, supporting a potential role for posttranscriptional regulation mediated by m(6)A in cancer. Here, we explore prostate cancer as an exemplar and demonstrate that...

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Detalles Bibliográficos
Autores principales: Cotter, Kellie A., Gallon, John, Uebersax, Nadine, Rubin, Philip, Meyer, Kate D., Piscuoglio, Salvatore, Jaffrey, Samie R., Rubin, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2021
Materias:
RNA Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349875/
https://www.ncbi.nlm.nih.gov/pubmed/34088870
http://dx.doi.org/10.1158/1541-7786.MCR-21-0014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349875/
https://www.ncbi.nlm.nih.gov/pubmed/34088870
http://dx.doi.org/10.1158/1541-7786.MCR-21-0014

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