The Innate Immune cGAS-STING-Pathway in Cardiovascular Diseases – A Mini Review

Inflammation plays a central role in cardiovascular diseases (CVD). One pathway under investigation is the innate immune DNA sensor cyclic GMP-AMP synthase (cGAS) and its downstream receptor stimulator of interferon genes (STING). cGAS-STING upregulates type I interferons in response to pathogens. R...

Descripción completa

Detalles Bibliográficos
Autores principales: Rech, Lavinia, Rainer, Peter P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349977/
https://www.ncbi.nlm.nih.gov/pubmed/34381828
http://dx.doi.org/10.3389/fcvm.2021.715903

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349977/
https://www.ncbi.nlm.nih.gov/pubmed/34381828
http://dx.doi.org/10.3389/fcvm.2021.715903

Ejemplares similares