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The Innate Immune cGAS-STING-Pathway in Cardiovascular Diseases – A Mini Review
Inflammation plays a central role in cardiovascular diseases (CVD). One pathway under investigation is the innate immune DNA sensor cyclic GMP-AMP synthase (cGAS) and its downstream receptor stimulator of interferon genes (STING). cGAS-STING upregulates type I interferons in response to pathogens. R...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349977/ https://www.ncbi.nlm.nih.gov/pubmed/34381828 http://dx.doi.org/10.3389/fcvm.2021.715903 |