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Quantitative MRI susceptibility mapping reveals cortical signatures of changes in iron, calcium and zinc in malformations of cortical development in children with drug-resistant epilepsy

OBJECTIVE: Malformations of cortical development (MCD), including focal cortical dysplasia (FCD), are the most common cause of drug-resistant focal epilepsy in children. Histopathological lesion characterisation demonstrates abnormal cell types and lamination, alterations in myelin (typically co-loc...

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Detalles Bibliográficos
Autores principales: Lorio, Sara, Sedlacik, Jan, So, Po-Wah, Parkes, Harold G., Gunny, Roxana, Löbel, Ulrike, Li, Yao-Feng, Ogunbiyi, Olumide, Mistry, Talisa, Dixon, Emma, Adler, Sophie, Cross, J. Helen, Baldeweg, Torsten, Jacques, Thomas S., Shmueli, Karin, Carmichael, David W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350142/
https://www.ncbi.nlm.nih.gov/pubmed/34058334
http://dx.doi.org/10.1016/j.neuroimage.2021.118102