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T2 heterogeneity as an in vivo marker of microstructural integrity in medial temporal lobe subfields in ageing and mild cognitive impairment

A better understanding of early brain changes that precede loss of independence in diseases like Alzheimer's disease (AD) is critical for development of disease-modifying therapies. Quantitative MRI, such as T2 relaxometry, can identify microstructural changes relevant to early stages of pathol...

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Detalles Bibliográficos
Autores principales: Wearn, Alfie R., Nurdal, Volkan, Saunders-Jennings, Esther, Knight, Michael J., Madan, Christopher R., Fallon, Sean-James, Isotalus, Hanna K., Kauppinen, Risto A., Coulthard, Elizabeth J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350145/
https://www.ncbi.nlm.nih.gov/pubmed/34116150
http://dx.doi.org/10.1016/j.neuroimage.2021.118214