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T2 heterogeneity as an in vivo marker of microstructural integrity in medial temporal lobe subfields in ageing and mild cognitive impairment
A better understanding of early brain changes that precede loss of independence in diseases like Alzheimer's disease (AD) is critical for development of disease-modifying therapies. Quantitative MRI, such as T2 relaxometry, can identify microstructural changes relevant to early stages of pathol...
Autores principales: | Wearn, Alfie R., Nurdal, Volkan, Saunders-Jennings, Esther, Knight, Michael J., Madan, Christopher R., Fallon, Sean-James, Isotalus, Hanna K., Kauppinen, Risto A., Coulthard, Elizabeth J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350145/ https://www.ncbi.nlm.nih.gov/pubmed/34116150 http://dx.doi.org/10.1016/j.neuroimage.2021.118214 |
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