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Metformin with neoadjuvant chemoradiation to improve pathologic response in rectal cancer: A pilot phase I/II trial

PURPOSE: Neoadjuvant radiotherapy with or without chemotherapy decreases the risk of local recurrence after surgery for rectal cancer. Emerging data suggest that diabetic patients on metformin may have improved cancer outcome after radiotherapy. A single institutional pilot study was performed to de...

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Detalles Bibliográficos
Autores principales: Wong, C.S., Chu, W., Ashamalla, S., Fenech, D., Berry, S., Kiss, A., Koritzinsky, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350187/
https://www.ncbi.nlm.nih.gov/pubmed/34401534
http://dx.doi.org/10.1016/j.ctro.2021.07.001