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Superiority of focused ion beam‐scanning electron microscope tomography of cardiomyocytes over standard 2D analyses highlighted by unmasking mitochondrial heterogeneity

BACKGROUND: Cardioprotection by preventing or repairing mitochondrial damage is an unmet therapeutic need. To understand the role of cardiomyocyte mitochondria in physiopathology, the reliable characterization of the mitochondrial morphology and compartment is pivotal. Previous studies mostly relied...

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Detalles Bibliográficos
Autores principales: Heinen‐Weiler, Jacqueline, Hasenberg, Mike, Heisler, Martin, Settelmeier, Stephan, Beerlage, Anna‐Lena, Doepper, Hannah, Walkenfort, Bernd, Odersky, Andrea, Luedike, Peter, Winterhager, Elke, Rassaf, Tienush, Hendgen‐Cotta, Ulrike B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350221/
https://www.ncbi.nlm.nih.gov/pubmed/34120411
http://dx.doi.org/10.1002/jcsm.12742