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Superiority of focused ion beam‐scanning electron microscope tomography of cardiomyocytes over standard 2D analyses highlighted by unmasking mitochondrial heterogeneity
BACKGROUND: Cardioprotection by preventing or repairing mitochondrial damage is an unmet therapeutic need. To understand the role of cardiomyocyte mitochondria in physiopathology, the reliable characterization of the mitochondrial morphology and compartment is pivotal. Previous studies mostly relied...
Autores principales: | Heinen‐Weiler, Jacqueline, Hasenberg, Mike, Heisler, Martin, Settelmeier, Stephan, Beerlage, Anna‐Lena, Doepper, Hannah, Walkenfort, Bernd, Odersky, Andrea, Luedike, Peter, Winterhager, Elke, Rassaf, Tienush, Hendgen‐Cotta, Ulrike B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350221/ https://www.ncbi.nlm.nih.gov/pubmed/34120411 http://dx.doi.org/10.1002/jcsm.12742 |
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