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Proprotein convertase subtilisin/kexin Type 9 is required for Ahnak-mediated metastasis of melanoma into lung epithelial cells

Previously we demonstrated that Ahnak mediates transforming growth factor-β (TGFβ)-induced epithelial-mesenchymal transition (EMT) during tumor metastasis. It is well-known that circulating tumor cells (CTCs) invade the vasculature of adjacent target tissues before working to adapt to the host envir...

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Detalles Bibliográficos
Autores principales: Suh, Jung Min, Son, Yelin, Yoo, Jung-Yeon, Goh, Yookyung, Seidah, Nabil G., Lee, Sanghyuk, Bae, Yun Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350332/
https://www.ncbi.nlm.nih.gov/pubmed/34352405
http://dx.doi.org/10.1016/j.neo.2021.07.007