Cross-talk among MEN1, p53 and Notch regulates the proliferation of pancreatic neuroendocrine tumor cells by modulating INSM1 expression and subcellular localization

Genomic analysis of Pancreatic Neuroendocrine Tumors (PanNETs) has revealed that these tumors often lack mutations in typical cancer-related genes such as the tumor suppressor gene p53. Instead, PanNET tumorigenesis usually involves mutations in specific PanNET-related genes, such as tumor suppresso...

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Detalles Bibliográficos
Autores principales: Capodanno, Ylenia, Chen, Yu, Schrader, Joerg, Tomosugi, Mitsuhiro, Sumi, Shoiciro, Yokoyama, Akihiko, Hiraoka, Nobuyoshi, Ohki, Rieko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350333/
https://www.ncbi.nlm.nih.gov/pubmed/34352404
http://dx.doi.org/10.1016/j.neo.2021.07.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350333/
https://www.ncbi.nlm.nih.gov/pubmed/34352404
http://dx.doi.org/10.1016/j.neo.2021.07.008

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