FOXM1-AKT Positive Regulation Loop Provides Venetoclax Resistance in AML

Forkhead box protein M1 (FOXM1) is a crucial regulator of cancer development and chemoresistance. It is often overexpressed in acute myeloid leukemia (AML) and is associated with poor survival and reduced efficacy of cytarabine therapy. Molecular mechanisms underlying high FOXM1 expression levels in...

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Detalles Bibliográficos
Autores principales: Chesnokov, Mikhail S, Borhani, Soheila, Halasi, Marianna, Arbieva, Zarema, Khan, Irum, Gartel, Andrei L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350342/
https://www.ncbi.nlm.nih.gov/pubmed/34381718
http://dx.doi.org/10.3389/fonc.2021.696532

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350342/
https://www.ncbi.nlm.nih.gov/pubmed/34381718
http://dx.doi.org/10.3389/fonc.2021.696532

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