Lovastatin Alleviates α-Synuclein Aggregation and Phosphorylation in Cellular Models of Synucleinopathy

Parkinson’s disease (PD) is one of the most common neurodegenerative diseases. Pathologically, it is characterized by the aberrant aggregation of α-synuclein (α-syn) in neurons. Clinical evidence shows that patients with hypercholesterolemia are more likely to get PD, while lovastatin users have a l...

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Detalles Bibliográficos
Autores principales: Dai, Lijun, Wang, Jiannan, He, Mingyang, Xiong, Min, Tian, Ye, Liu, Chaoyang, Zhang, Zhentao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350347/
https://www.ncbi.nlm.nih.gov/pubmed/34381332
http://dx.doi.org/10.3389/fnmol.2021.682320

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350347/
https://www.ncbi.nlm.nih.gov/pubmed/34381332
http://dx.doi.org/10.3389/fnmol.2021.682320

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