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Lovastatin Alleviates α-Synuclein Aggregation and Phosphorylation in Cellular Models of Synucleinopathy
Parkinson’s disease (PD) is one of the most common neurodegenerative diseases. Pathologically, it is characterized by the aberrant aggregation of α-synuclein (α-syn) in neurons. Clinical evidence shows that patients with hypercholesterolemia are more likely to get PD, while lovastatin users have a l...
Autores principales: | Dai, Lijun, Wang, Jiannan, He, Mingyang, Xiong, Min, Tian, Ye, Liu, Chaoyang, Zhang, Zhentao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350347/ https://www.ncbi.nlm.nih.gov/pubmed/34381332 http://dx.doi.org/10.3389/fnmol.2021.682320 |
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