A new model for sensitive detection of zoonotic prions by PrP transgenic Drosophila

Prions are transmissible protein pathogens most reliably detected by a bioassay in a suitable host, typically mice. However, the mouse bioassay is slow and cumbersome, and relatively insensitive to low titers of prion infectivity. Prions can be detected biochemically in vitro by the protein misfoldi...

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Detalles Bibliográficos
Autores principales: Thackray, Alana M., Andréoletti, Olivier, Spiropoulos, John, Bujdoso, Raymond
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350378/
https://www.ncbi.nlm.nih.gov/pubmed/34270959
http://dx.doi.org/10.1016/j.jbc.2021.100878

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350378/
https://www.ncbi.nlm.nih.gov/pubmed/34270959
http://dx.doi.org/10.1016/j.jbc.2021.100878

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