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Solution Structure of the dATP-Inactivated Class I Ribonucleotide Reductase From Leeuwenhoekiella blandensis by SAXS and Cryo-Electron Microscopy

The essential enzyme ribonucleotide reductase (RNR) is highly regulated both at the level of overall activity and substrate specificity. Studies of class I, aerobic RNRs have shown that overall activity is downregulated by the binding of dATP to a small domain known as the ATP-cone often found at th...

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Detalles Bibliográficos
Autores principales: Hasan, Mahmudul, Banerjee, Ipsita, Rozman Grinberg, Inna, Sjöberg, Britt-Marie, Logan, Derek T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350387/
https://www.ncbi.nlm.nih.gov/pubmed/34381817
http://dx.doi.org/10.3389/fmolb.2021.713608