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Membrane interaction and disulphide-bridge formation in the unconventional secretion of Tau

Misfolded, pathological tau protein propagates from cell to cell causing neuronal degeneration in Alzheimer’s disease and other tauopathies. The molecular mechanisms of this process have remained elusive. Unconventional secretion of tau takes place via several different routes, including direct pene...

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Detalles Bibliográficos
Autores principales: Hellén, Marianna, Bhattacharjee, Arnab, Uronen, Riikka-Liisa, Huttunen, Henri J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350431/
https://www.ncbi.nlm.nih.gov/pubmed/34308969
http://dx.doi.org/10.1042/BSR20210148