Validation of Single Nucleotide Variant Assays for Human Leukocyte Antigen Haplotypes HLA-B*15:02 and HLA-A*31:01 Across Diverse Ancestral Backgrounds

The human leukocyte antigen haplotypes HLA-B*15:02 and HLA-A*31:01 have been linked to life-threatening adverse drug reactions to the anticonvulsants carbamazepine and oxcarbazepine. Identification of these haplotypes via pharmacogenetic techniques facilitates implementation of precision medicine to...

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Detalles Bibliográficos
Autores principales: Buchner, Amanda, Hu, Xiuying, Aitchison, Katherine J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350439/
https://www.ncbi.nlm.nih.gov/pubmed/34381365
http://dx.doi.org/10.3389/fphar.2021.713178

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350439/
https://www.ncbi.nlm.nih.gov/pubmed/34381365
http://dx.doi.org/10.3389/fphar.2021.713178

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