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Development of a putative adverse outcome pathway network for male rat reproductive tract abnormalities with specific considerations for the androgen sensitive window of development

Structured approaches like the adverse outcome pathway (AOP) framework offer great potential for depicting complex toxicological processes in a manner that can facilitate informed integration of mechanistic information in regulatory decisions. While this concept provides a structure for organizing e...

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Detalles Bibliográficos
Autores principales: Palermo, Christine M., Foreman, Jennifer E., Wikoff, Daniele S., Lea, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350458/
https://www.ncbi.nlm.nih.gov/pubmed/34401750
http://dx.doi.org/10.1016/j.crtox.2021.07.002