Malate-Aspartate Shuttle Plays an Important Role in LPS-Induced Neuroinflammation of Mice Due to its Effect on STAT3 Phosphorylation

Neuroinflammation is a key pathological factor in numerous neurological disorders. Cumulating evidence has indicated critical roles of NAD(+)/NADH metabolism in multiple major diseases, while the role of malate-aspartate shuttle (MAS) - a major NADH shuttle - in inflammation has remained unclear. In...

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Detalles Bibliográficos
Autores principales: Zhou, Cuiyan, Shang, Wangsong, Yin, Shan-Kai, Shi, Haibo, Ying, Weihai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350486/
https://www.ncbi.nlm.nih.gov/pubmed/34381810
http://dx.doi.org/10.3389/fmolb.2021.655687

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350486/
https://www.ncbi.nlm.nih.gov/pubmed/34381810
http://dx.doi.org/10.3389/fmolb.2021.655687

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