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Role of acetylation in doxorubicin-induced cardiotoxicity

As a potent chemotherapeutic agent, doxorubicin (DOX) is widely used for the treatment of a variety of cancers However, its clinical utility is limited by dose-dependent cardiotoxicity, and pathogenesis has traditionally been attributed to the formation of reactive oxygen species (ROS). Accordingly,...

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Detalles Bibliográficos
Autores principales: Li, Daisong, Yang, Yanyan, Wang, Shizhong, He, Xiangqin, Liu, Meixin, Bai, Baochen, Tian, Chao, Sun, Ruicong, Yu, Tao, Chu, Xianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350499/
https://www.ncbi.nlm.nih.gov/pubmed/34364220
http://dx.doi.org/10.1016/j.redox.2021.102089