NANOS2 suppresses the cell cycle by repressing mTORC1 activators in embryonic male germ cells

During murine germ cell development, male germ cells enter the mitotically arrested G0 stage, which is an initial step of sexually dimorphic differentiation. The male-specific RNA-binding protein NANOS2 has a key role in suppressing the cell cycle in germ cells. However, the detailed mechanism of ho...

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Detalles Bibliográficos
Autores principales: Shimada, Ryuki, Koike, Hiroko, Hirano, Takamasa, Kato, Yuzuru, Saga, Yumiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350546/
https://www.ncbi.nlm.nih.gov/pubmed/34401671
http://dx.doi.org/10.1016/j.isci.2021.102890

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350546/
https://www.ncbi.nlm.nih.gov/pubmed/34401671
http://dx.doi.org/10.1016/j.isci.2021.102890

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