Cargando…

CHIP-dependent regulation of the actin cytoskeleton is linked to neuronal cell membrane integrity

Mostrar otras versiones (1)

CHIP is an E3-ubiquitin ligase that contributes to healthy aging and has been characterized as neuroprotective. To elucidate dominant CHIP-dependent changes in protein steady-state levels in a patient-derived human neuronal model, CHIP function was ablated using gene-editing and an unbiased proteomi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dias, Catarina, Nita, Erisa, Faktor, Jakub, Tynan, Ailish C., Hernychova, Lenka, Vojtesek, Borivoj, Nylandsted, Jesper, Hupp, Ted R., Kunath, Tilo, Ball, Kathryn L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350547/ https://www.ncbi.nlm.nih.gov/pubmed/34401662 http://dx.doi.org/10.1016/j.isci.2021.102878

Ejemplares similares

CHIP-dependent regulation of the actin cytoskeleton is linked to neuronal cell membrane integrity
por: Dias, Catarina, et al.
Publicado: (2022)

Generation of a CHIP isogenic human iPSC-derived cortical neuron model for functional proteomics
por: Dias, Catarina, et al.
Publicado: (2022)

The effects of IFITM1 and IFITM3 gene deletion on IFNγ stimulated protein synthesis
por: Gómez-Herranz, Maria, et al.
Publicado: (2019)

Emergent Role of IFITM1/3 towards Splicing Factor (SRSF1) and Antigen-Presenting Molecule (HLA-B) in Cervical Cancer
por: Gómez-Herranz, Maria, et al.
Publicado: (2022)

Hydrogen deuterium exchange mass spectrometry identifies the dominant paratope in CD20 antigen binding to the NCD1.2 monoclonal antibody
por: Uhrik, Lukas, et al.
Publicado: (2021)

Rearrangement of mitochondrial pyruvate dehydrogenase subunit dihydrolipoamide dehydrogenase protein–protein interactions by the MDM2 ligand nutlin‐3
por: Way, Luke, et al.
Publicado: (2016)

The MDM2 ligand Nutlin-3 differentially alters expression of the immune blockade receptors PD-L1 and CD276
por: Li, Ruidong, et al.
Publicado: (2020)

The Sequence-specific Peptide-binding Activity of the Protein Sulfide Isomerase AGR2 Directs Its Stable Binding to the Oncogenic Receptor EpCAM
por: Mohtar, M. Aiman, et al.
Publicado: (2018)

Kinomics platform using GBM tissue identifies BTK as being associated with higher patient survival
por: Al Shboul, Sofian, et al.
Publicado: (2021)

Hammock: a hidden Markov model-based peptide clustering algorithm to identify protein-interaction consensus motifs in large datasets
por: Krejci, Adam, et al.
Publicado: (2016)

IFITM protein regulation and functions: Far beyond the fight against viruses
por: Friedlová, Nela, et al.
Publicado: (2022)

Next-generation sequencing of a combinatorial peptide phage library screened against ubiquitin identifies peptide aptamers that can inhibit the in vitro ubiquitin transfer cascade
por: Lisowska, Małgorzata, et al.
Publicado: (2022)

Actin Cytoskeletal Dynamics in Single-Cell Wound Repair
por: Ebstrup, Malene Laage, et al.
Publicado: (2021)

Surface-enhanced laser desorption/ionization time-of-flight proteomic profiling of breast carcinomas identifies clinicopathologically relevant groups of patients similar to previously defined clusters from cDNA expression
por: Brozkova, Kristyna, et al.
Publicado: (2008)

The new platinum-based anticancer agent LA-12 induces retinol binding protein 4 in vivo
por: Bouchal, Pavel, et al.
Publicado: (2011)

Alterations of the Hsp70/Hsp90 chaperone and the HOP/CHIP co-chaperone system in cancer
por: Ruckova, Eva, et al.
Publicado: (2012)

Plasma membrane integrity in health and disease: significance and therapeutic potential
por: Dias, Catarina, et al.
Publicado: (2021)

Identification of novel interferon responsive protein partners of human leukocyte antigen A (HLA-A) using cross-linking mass spectrometry (CLMS) approach
por: Singh, Ashita, et al.
Publicado: (2022)

HCMV pUL135 Remodels the Actin Cytoskeleton to Impair Immune Recognition of Infected Cells
por: Stanton, Richard J., et al.
Publicado: (2014)

Actin cytoskeleton in angiogenesis
por: Yadunandanan Nair, Nidhi, et al.
Publicado: (2022)

Allosteric changes in HDM2 by the ATM phosphomimetic S395D mutation: implications on HDM2 function
por: Uhrik, Lukas, et al.
Publicado: (2019)

Unraveling the actin cytoskeleton in the malignant transformation of cholangiocyte biology
por: Duwe, Lea, et al.
Publicado: (2022)

A blocking antibody against canine CSF-1R maturated by limited CDR mutagenesis
por: Beirão, Breno C B, et al.
Publicado: (2020)

Dynamic reorganization of the actin cytoskeleton
por: Letort, Gaëlle, et al.
Publicado: (2015)

Regulation of the Actin Cytoskeleton in Podocytes
por: Blaine, Judith, et al.
Publicado: (2020)

An integrated DNA and RNA variant detector identifies a highly conserved three base exon in the MAP4K5 kinase locus
por: Kurkowiak, Małgorzata, et al.
Publicado: (2021)

Cryptic in vitro ubiquitin ligase activity of HDMX towards p53 is probably regulated by an induced fit mechanism
por: Calderon-González, Karla Gisel, et al.
Publicado: (2022)

Identification of Cytoskeleton-Associated Proteins Essential for Lysosomal Stability and Survival of Human Cancer Cells
por: Groth-Pedersen, Line, et al.
Publicado: (2012)

Actin Cytoskeleton Regulates Hippo Signaling
por: Reddy, Pradeep, et al.
Publicado: (2013)

Regulation and integrated functions of the actin cytoskeleton
por: Charras, Guillaume, et al.
Publicado: (2016)

Regulation of Mitochondrial Function by the Actin Cytoskeleton
por: Illescas, María, et al.
Publicado: (2021)

Dynamics of the Actin Cytoskeleton at Adhesion Complexes
por: Cronin, Nicholas M., et al.
Publicado: (2021)

Actin-Myosin Cytoskeleton Regulation and Function
por: Olson, Michael F.
Publicado: (2022)

Apoptosis in platelets is independent of the actin cytoskeleton
por: De Silva, Enoli, et al.
Publicado: (2022)

TRPV2 interacts with actin and reorganizes submembranous actin cytoskeleton
por: Yadav, Manoj, et al.
Publicado: (2020)

Actin-Associated Proteins and Small Molecules Targeting the Actin Cytoskeleton
por: Gao, Jing, et al.
Publicado: (2022)

Interfaces with Structure Dynamics of the Workhorses from Cells Revealed through Cross-Linking Mass Spectrometry (CLMS)
por: Kalathiya, Umesh, et al.
Publicado: (2021)

ΔNp63 transcriptionally regulates ATM to control p53 Serine-15 phosphorylation
por: Craig, Ashley L, et al.
Publicado: (2010)

Molecular Links between Endocytosis and the Actin Cytoskeleton
por: Qualmann, Britta, et al.
Publicado: (2000)

Functional interdependence between septin and actin cytoskeleton
por: Schmidt, Katja, et al.
Publicado: (2004)

Cannot write session to /tmp/vufind_sessions/sess_knoehv3ou8tfkp8rtmk7esfik8