SMAD4 represses FOSL1 expression and pancreatic cancer metastatic colonization

Metastasis is a complex and poorly understood process. In pancreatic cancer, loss of the transforming growth factor (TGF)-β/BMP effector SMAD4 is correlated with changes in altered histopathological transitions, metastatic disease, and poor prognosis. In this study, we use isogenic cancer cell lines...

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Detalles Bibliográficos
Autores principales: Dai, Chao, Rennhack, Jonathan P., Arnoff, Taylor E., Thaker, Maneesha, Younger, Scott T., Doench, John G., Huang, August Yue, Yang, Annan, Aguirre, Andrew J., Wang, Belinda, Mun, Evan, O’Connell, Joyce T., Huang, Ying, Labella, Katherine, Talamas, Jessica A., Li, Ji, Ilic, Nina, Hwang, Justin, Hong, Andrew L., Giacomelli, Andrew O., Gjoerup, Ole, Root, David E., Hahn, William C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350598/
https://www.ncbi.nlm.nih.gov/pubmed/34320363
http://dx.doi.org/10.1016/j.celrep.2021.109443

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350598/
https://www.ncbi.nlm.nih.gov/pubmed/34320363
http://dx.doi.org/10.1016/j.celrep.2021.109443

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