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Chemerin/ChemR23 signaling mediates the effects of ultra-high molecular weight polyethylene wear particles on the balance between osteoblast and osteoclast differentiation

BACKGROUND: Ultra-high molecular weight polyethylene (UHMWPE) is one of the favored materials for total joint replacement, but its wear particles cause osteolysis. This study aims to elucidate the signaling that mediates the effects of UHMWPE particles on bone cells. METHODS: RAW264.7 and MC3T3-E1 c...

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Detalles Bibliográficos
Autores principales: Zhao, Fengchao, Cang, Dingwei, Zhang, Jianzhi, Zheng, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350637/
https://www.ncbi.nlm.nih.gov/pubmed/34430590
http://dx.doi.org/10.21037/atm-21-2945