TGR5 protects against cholestatic liver disease via suppressing the NF-κB pathway and activating the Nrf2/HO-1 pathway

BACKGROUND: Characterized by the presence of inflammation, fibrosis, and bile duct proliferation, cholestatic liver disease (CLD) affects people of all age groups. Takeda G-protein-coupled receptor (TGR5) has been implicated in the suppression of inflammation via toll-like receptor 4 (TLR4) and nucl...

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Detalles Bibliográficos
Autores principales: Yang, Haojun, Luo, Fengyong, Wei, Yi, Jiao, Yuwen, Qian, Jun, Chen, Shuai, Gong, Yu, Tang, Liming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350648/
https://www.ncbi.nlm.nih.gov/pubmed/34430599
http://dx.doi.org/10.21037/atm-21-2631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350648/
https://www.ncbi.nlm.nih.gov/pubmed/34430599
http://dx.doi.org/10.21037/atm-21-2631

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