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TGR5 protects against cholestatic liver disease via suppressing the NF-κB pathway and activating the Nrf2/HO-1 pathway
BACKGROUND: Characterized by the presence of inflammation, fibrosis, and bile duct proliferation, cholestatic liver disease (CLD) affects people of all age groups. Takeda G-protein-coupled receptor (TGR5) has been implicated in the suppression of inflammation via toll-like receptor 4 (TLR4) and nucl...
Autores principales: | Yang, Haojun, Luo, Fengyong, Wei, Yi, Jiao, Yuwen, Qian, Jun, Chen, Shuai, Gong, Yu, Tang, Liming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350648/ https://www.ncbi.nlm.nih.gov/pubmed/34430599 http://dx.doi.org/10.21037/atm-21-2631 |
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