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Pharmacokinetics of treprostinil in children with functional single-ventricle pulmonary arterial hypertension: a randomized controlled trial

BACKGROUND: Application of Treprostinil (TRE) in the patients with single ventricle (SV) physiology is very limited, and the optimal dose for children has not been determined. In this study, we aimed to analyze plasma samples to assess the attainment of clinically therapeutic concentrations of TRE a...

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Detalles Bibliográficos
Autores principales: Chen, Xi, Cai, Xiao-Man, Zhang, Ming-Jie, Xu, Jing-Han, Li, Hao, Xu, Zhuo-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350654/
https://www.ncbi.nlm.nih.gov/pubmed/34430604
http://dx.doi.org/10.21037/atm-21-3188