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Novel ETV1 mutation in small cell lung cancer transformation resistant to EGFR tyrosine kinase inhibitors

BACKGROUND: Non-small cell lung cancer (NSCLC) patients harboring mutations in the epidermal growth factor receptor (EGFR) gene respond dramatically to EGFR tyrosine kinase inhibitors (TKIs). However, these patients inevitably develop acquired resistance to EGFR-TKIs. Among them, small cell lung can...

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Detalles Bibliográficos
Autores principales: Zhou, Yan, Bai, Hao, Xia, Jinjing, Xu, Wang-Yang, Cheng, Lei, Xiong, Liwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350694/
https://www.ncbi.nlm.nih.gov/pubmed/34430591
http://dx.doi.org/10.21037/atm-21-2625