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Azithromycin induces apoptosis in airway smooth muscle cells through mitochondrial pathway in a rat asthma model

BACKGROUND: The proliferation of airway smooth muscle cells (ASMCs) is a key feature of airway remodeling in asthma. Azithromycin (AZM) has been shown to decrease bronchial hyperresponsiveness and airway inflammation in asthmatics; however, the role of AZM in ASMC proliferation remains unclear. Thus...

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Detalles Bibliográficos
Autores principales: Wu, Liqin, Yin, Juan, Zhang, Qi, Wang, Meiyan, Dai, Wei, Zhou, Jian, Dai, Yuanrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350718/
https://www.ncbi.nlm.nih.gov/pubmed/34430622
http://dx.doi.org/10.21037/atm-21-3478