Combination Therapy of Mithramycin A and Immune Checkpoint Inhibitor for the Treatment of Colorectal Cancer in an Orthotopic Murine Model

The axis of Programmed cell death-1 receptor (PD-1) with its ligand (PD-L1) plays a critical role in colorectal cancer (CRC) in escaping immune surveillance, and blocking this axis has been found to be effective in a subset of patients. Although blocking PD-L1 has been shown to be effective in 5–10%...

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Detalles Bibliográficos
Autores principales: Dutta, Rinku, Khalil, Roukiah, Mayilsamy, Karthick, Green, Ryan, Howell, Mark, Bharadwaj, Srinivas, Mohapatra, Shyam S., Mohapatra, Subhra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350740/
https://www.ncbi.nlm.nih.gov/pubmed/34381456
http://dx.doi.org/10.3389/fimmu.2021.706133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350740/
https://www.ncbi.nlm.nih.gov/pubmed/34381456
http://dx.doi.org/10.3389/fimmu.2021.706133

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