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Fragmentation patterns and personalized sequencing of cell‐free DNA in urine and plasma of glioma patients

Glioma‐derived cell‐free DNA (cfDNA) is challenging to detect using liquid biopsy because quantities in body fluids are low. We determined the glioma‐derived DNA fraction in cerebrospinal fluid (CSF), plasma, and urine samples from patients using sequencing of personalized capture panels guided by a...

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Detalles Bibliográficos
Autores principales: Mouliere, Florent, Smith, Christopher G, Heider, Katrin, Su, Jing, van der Pol, Ymke, Thompson, Mareike, Morris, James, Wan, Jonathan C M, Chandrananda, Dineika, Hadfield, James, Grzelak, Marta, Hudecova, Irena, Couturier, Dominique‐Laurent, Cooper, Wendy, Zhao, Hui, Gale, Davina, Eldridge, Matthew, Watts, Colin, Brindle, Kevin, Rosenfeld, Nitzan, Mair, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350897/
https://www.ncbi.nlm.nih.gov/pubmed/34291583
http://dx.doi.org/10.15252/emmm.202012881